Memarian e_Learning Institute



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Inherited mutations may play a role in pancreatic cancer development

A small, retrospective study has found that, in patients with particular pancreatic duct lesions, the presence of an inherited mutation in a pancreatic cancer susceptibility gene may increase the patients' risk of developing pancreatic cancer.


Michael Skaro, Neha Nanda, Christian Gauthier, Matthäus Felsenstein, Zhengdong Jiang, Miaozhen Qiu, Koji Shindo, Jun Yu, Danielle Hutchings, Ammar A. Javed, Ross Beckman, Jin He, Christopher L. Wolfgang, Elizabeth Thompson, Ralph H. Hruban, Alison P. Klein, Michael Goggins, Laura D. Wood, Nicholas J. Roberts. Prevalence of Germline Mutations Associated with Cancer Risk in Patients With Intraductal Papillary Mucinous Neoplasms. Gastroenterology, 2019; DOI: 10.1053/j.gastro.2019.01.254

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