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02/28/2019

Improved outlook for people of African descent with treatment-resistant schizophrenia

A new study means that more people of African descent who have treatment-resistant schizophrenia could be safely given the drug best proven to manage their symptoms.


Source: https://www.sciencedaily.com/releases/2019/02/190226112327.htm

Sophie E. Legge, Antonio F. Pardiñas, Marinka Helthuis, John A. Jansen, Karel Jollie, Steven Knapper, James H. MacCabe, Dan Rujescu, David A. Collier, Michael C. O’Donovan, Michael J Owen, James T. R. Walters. A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related neutropenia. Molecular Psychiatry, 2019; 24 (3): 328 DOI: 10.1038/s41380-018-0335-7



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