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03/03/2019

Mechanism behind DNA damage control uncovered

Researchers have identified a mechanism that is critical for the survival of cells under genotoxic stress. New finding could help develop novel anti-cancer approaches to improve the cancer cell killing effects of chemotherapy.


Source: https://www.sciencedaily.com/releases/2019/02/190226112344.htm

Andrii Bugai, Alexandre J.C. Quaresma, Caroline C. Friedel, Tina Lenasi, Robert Düster, Christopher R. Sibley, Koh Fujinaga, Petra Kukanja, Thomas Hennig, Melanie Blasius, Matthias Geyer, Jernej Ule, Lars Dölken, Matjaž Barborič. P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Response to Genotoxic Stress. Molecular Cell, 2019; DOI: 10.1016/j.molcel.2019.01.033



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